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Ovarian Cancer

Intraperitoneal Chemotherapy Improves Ovarian Cancer Survival

March 24, 2015
  • Leah Lawrence

The use of intraperitoneal chemotherapy for the treatment of advanced ovarian cancer resulted in a survival benefit over intravenous chemotherapy.

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Early-Onset Alopecia May Signal Chemotherapy Response for Ovarian Cancer

March 18, 2015
  • Leah Lawrence

Onset of alopecia within the first 3 cycles of chemotherapy was associated with improved survival in ovarian cancer patients who completed 6 cycles of chemo.

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Possible Target Found in ARID1A-Mutated Ovarian Cancers

March 12, 2015
  • Leah Lawrence

Researchers have discovered that ovarian cancers with ARID1A mutations may be sensitive to treatment with an inhibitor of EZH2 methyltransferase activity.

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Ovarian Cancer Disease Burden Affects Survival Despite R0 Resection

February 10, 2015
  • Leah Lawrence

Despite achieving complete surgical resection, advanced epithelial ovarian cancer or primary peritoneal cancer patients with a high disease burden had worse survival outcomes than those with lower disease burden.

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Advancements in Gynecological Oncology

January 27, 2015
  • Melissa Lind

Could the approval of bevacizumab for advanced cervical cancer and platinum-resistant ovarian cancer last year lead to patient-specific therapies?

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Veliparib Trial Fails to Improve Outcomes in Ovarian Cancer

January 23, 2015
  • Leah Lawrence

Adding the PARP inhibitor veliparib to cyclophosphamide did not improve response rates or progression-free survival in ovarian cancer.

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ACOG Recommends Salpingectomy for Ovarian Cancer Prevention

January 6, 2015
  • Leah Lawrence

ACOG recently released a Committee Opinion on the use of salpingectomy for ovarian cancer prevention in at-risk women undergoing routine pelvic surgery.

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FDA Approves New Drug for Advanced Ovarian Cancer

January 1, 2015
  • OBGYN.net Staff

The FDA has approved olaparib, to be marketed under the name Lynparza, for the treatment of advanced ovarian cancer related to defective BRCA genes.

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Oral Contraceptives May Reduce BRCA-Associated Ovarian Cancer Risk

December 18, 2014
  • Leah Lawrence

Researchers have identified several factors, including breastfeeding and oral contraceptives, that may decrease the risk of BRCA-associated ovarian cancer.

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Ovarian Cancer Cells Found With Tampon Detection Method

November 6, 2014
  • Leah Lawrence

Ovarian cancer cells were detected by collecting and testing DNA specimens taken from the tampons of ovarian cancer patients prior to surgery for a pelvic mass.

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