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Leah Lawrence

PCV13: Effective Against First-Episode CAP in Older Adults

April 20, 2015
  • Leah Lawrence

The 13-valent pneumococcal conjugate vaccine reduced nearly by half vaccine-type community acquired pneumonia in adults aged 65 years and older.

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Intraperitoneal Chemotherapy Improves Ovarian Cancer Survival

March 24, 2015
  • Leah Lawrence

The use of intraperitoneal chemotherapy for the treatment of advanced ovarian cancer resulted in a survival benefit over intravenous chemotherapy.

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Early-Onset Alopecia May Signal Chemotherapy Response for Ovarian Cancer

March 18, 2015
  • Leah Lawrence

Onset of alopecia within the first 3 cycles of chemotherapy was associated with improved survival in ovarian cancer patients who completed 6 cycles of chemo.

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Possible Target Found in ARID1A-Mutated Ovarian Cancers

March 12, 2015
  • Leah Lawrence

Researchers have discovered that ovarian cancers with ARID1A mutations may be sensitive to treatment with an inhibitor of EZH2 methyltransferase activity.

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GLP-1 Receptor Agonists and Cardiovascular Outcomes: 3 Studies

February 20, 2015
  • Leah Lawrence

Cardiovascular disease is the underlying cause of death in more than 60% of patients with T2DM. GLP-1 receptor agonists have shown promising cardioprotective effects.

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Ovarian Cancer Disease Burden Affects Survival Despite R0 Resection

February 10, 2015
  • Leah Lawrence

Despite achieving complete surgical resection, advanced epithelial ovarian cancer or primary peritoneal cancer patients with a high disease burden had worse survival outcomes than those with lower disease burden.

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Early Natural Menopause Ups Risk of Heart Failure

February 2, 2015
  • Leah Lawrence

Women who experience menopause before age 46 have an increased risk of heart disease, and smoking status can modifying this risk in older women.

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Veliparib Trial Fails to Improve Outcomes in Ovarian Cancer

January 23, 2015
  • Leah Lawrence

Adding the PARP inhibitor veliparib to cyclophosphamide did not improve response rates or progression-free survival in ovarian cancer.

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The Utility of Vaginal Estrogens for Managing GSM

January 21, 2015
  • Leah Lawrence

Vaginal estrogens are effective options for managing bothersome symptoms related to genitourinary syndrome of menopause in postmenopausal women.

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Second-Line Ramucirumab Plus Chemotherapy Improved Survival in Metastatic Colorectal Cancer

January 13, 2015
  • Leah Lawrence

The addition of ramucirumab to second-line FOLFIRI resulted in a delay in disease progression and improved survival in metastatic colorectal cancer patients.

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