In the past year, my staff and I have seen a dramatic increase in the use of both marijuana and electronic cigarettes, or e-cigarettes, among our patients, consistent with nationwide trends. As a result, we now include very specific questions about their use on our intake forms as well as in our patient interviews.
Marijuana use has been on the rise among adolescents for many years. From 2008 to 2009, the rate of current illicit drug use among young adults aged 18 to 25 climbed 8%, from 19.6% to 21.2%, driven largely by a 10% rise in marijuana use (from 16.5% to 18.1%).1 At the time of that survey, 16.7 million people aged 12 years and older had used marijuana in the past month.
When speaking to my own patients, I find that adolescents (and adults) in my practice generally regard marijuana use as equivalent to alcohol use in their daily lives; this underestimation of harm is echoed in national surveys as well. However, marijuana has evolved since it first gained wide popularity in the United States in the 1960s. Through genetic manipulation, the potency of marijuana has doubled from 1998 to 2008.1
Marijuana is now a very different drug than it once was, with a much higher potential for addiction and harm. Studies have suggested an association between chronic marijuana use and increased rates of anxiety, depression, suicidal thoughts, and schizophrenia. Other research has shown marijuana smoke to contain carcinogens and to be an irritant to the lungs. In a prospective birth cohort study, researchers showed that, among adolescent initiators of marijuana use in New Zealand, persistent cannabis use was associated “with neuropsychological decline broadly across domains of functioning, even after controlling for years of education, suggesting a neurotoxic effect of cannabis on the adolescent brain.”2
Use of electronic cigarettes, or e-cigarettes, is on the rise as well. E-cigarettes, also known as vaping pens or hooka pens, are being aggressively marketed to younger users. According to the CDC, e-cigarettes are battery-powered devices that provide doses of nicotine and other additives to the user in an aerosol.3 E-cigarette cartridges typically contain nicotine; a component to produce the aerosol, generally either propylene glycol or glycerol; and flavorings, such as fruit, mint, or chocolate.3 The percentage of high school students who reported ever using an e-cigarette rose from 4.7% in 2011 to 10% in 2012.4 Altogether in 2012, more than 1.78 million middle and high school students nationwide had tried e-cigarettes.4
It is well known that early addiction to nicotine, regardless of the delivery system, is more likely to produce addictive behavior. The effects of nicotine on the adolescent brain are quite different than those in adults, according to Theodore Slotkin, PhD. “Adolescence represents a unique period of vulnerability for nicotine-induced mis-programming of brain cell development and synaptic function. Effects of nicotine on critical components of reward pathways and circuits involved in learning, memory and mood are likely to contribute to increased addictive properties and long term behavioral problems seen in adolescent smokers.”5
1. Office of National Drug Control Policy. Marijuana: Know the Facts. October 2010. Available at: http://www.whitehouse.gov/sites/default/files/ondcp/Fact_Sheets/marijuana_fact_sheet_jw_10-5-10.pdf. Accessed April 3, 2014.
2. Meier MH, Caspi A, Ambler A, et al. Persistent cannabis users show neuropsychological decline from childhood to midlife. Proc Natl Acad Sci U S A. 2012; doi: 10.1073/pnas.1206820109.
3. Centers for Disease Control and Prevention. Notes from the field: electronic cigarette use among middle and high school students—United States, 2011–2012. MMWR. September 6, 2013;62(35);729-730. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6235a6.htm. Accessed April 3, 2014.
4. Centers for Disease Control and Prevention. Tobacco product use among middle and high school sudents—United States, 2011 and 2012. 2013;62(45):893-897. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6245a2.htm. Accessed April 3, 2014.
5. Slotkin TA. Nicotine and the adolescent brain: insights from an animal model. Neurotoxicol Teratol. 2002;24:369-384.
6. Elliott D, for National Public Radio. E-Cigarette critics worry new ads will make 'vaping' cool for kids. March 3, 2014. Available at: http://www.npr.org/2014/03/03/284006424/e-cigarette-critics-worry-new-ads-will-make-vaping-cool-for-kids. Accessed April 3, 2014.
7. Chatham-Stephens K, Law R, Taylor E, et al. Notes from the field: calls to poison centers for exposures to electronic cigarettes—United States, September 2010–February 2014. MMWR. 2014;63(13):292-293. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6313a4.htm?s_cid=mm6313a4_e