medical professionals, women's health, obstetrics, gynecology, infertility, pregnancy, hysterectomy, fibroids, and more

 

Print this page
OBGYN.net Advertisement
OBGYN.net - Using RU 486

Dr. Joel Kompanietz, a practicing Ob/Gyn in France, offers his experience using RU 486.

Dr Joel Kompanietz, MD


Centre Hospitalier BP 538
81207 Mazamet cedex - France
Email: joel@horus-medical.fr

RU 486, called Myfegine in France, seems to be a good product. In abortion, we use it no later than 7 weeks of amenorhea, so women will have to hurry for consultation or to have surgery.
Success rate is 95-98 %:
If the RU 486 abortion sequence fails, surgery is imperative due to possible malformative effects.
Before using RU 486, you must have an echography to confirm the intra-uterine localisation of the pregnancy. RU 486 is not advised for extra-uterine pregnancies.

  • administer orally - 3 cp. of RU 486
  • wait 48 hours
  • administer orally - 2 cp. of misoprostol
  • Monitor the patient for a few hours, after administering the misoprostol, for possible vomiting and low blood pressure. We keep patients under observation 4 hours before they are sent home.
    There are two ways to examine for results: echography or HCG. I use HCG, as echography may not show anything this early in pregnancy.
    Patients over the age of 35 or that smoke can not use RU 486 - one death from cardio-vascular complications has been reported. Women under 35 years old must stop smoking during the RU 486 abortion sequence.

    In cases when the fetus has died in the womb
  • Administer 3 cp a day for 2 days
  • If no signs of labor in 72 hours use the prostaglandins. Adhere to standard care of prostaglandins usage.
  • NOTE: the use of RU 486 decreases, by 60 %, the rate of prostaglandins required to get expulsion.

    In medical pregnancy interruption (later in pregnancy than voluntary abortions):
  • Administer 3 cp of RU 486
  • 36 to 48 hours later administer usual prostaglandins.
  • NOTE: RU 486 decreases the rate of prostaglandins needed.

    For additional reference see:
    New England Journal of Medicine - April 13, 1995 -- Volume 332, Number 15: Induction of Abortion with Mifepristone (RU 486) and Oral or Vaginal Misoprostol.
    Hazem El-Refaey, Dhamnasekar Rajasekar, Mona Abdalla, Lynda Calder, Allan Templeton.