Higher serum polychlorinated biphenyl (PCB) concentration levels that are within the normal range for women in the general U.S. population are associated with failed implantation in women undergoing in vitro fertilization (IVF), according to a study published online Feb. 24 in Environmental Health Perspectives.
Is there a way to predict which patients will have the best outcomes following an assisted reproductive intervention? Dr William Gibbons, director of the Family Fertility Program at Texas Children’s Hospital and professor of obstetrics and gynecology at Baylor College of Medicine, and colleagues examined birth weight and gestational age of singleton pregnancies from in vitro fertilization, donor egg, and gestational carrier cycles to determine which factors most influence outcomes.
Progesterone support during the luteal phase is needed to allow for implementation in medically assisted cycles. To date, available options have not met all of the ideals of the “perfect” progesterone strategy—easy to administer, safe with minimal adverse effects, and effective in producing pregnancies.
The fertility field has seen incredible successes with in vitro fertilization and intracytoplasmic sperm injection. However, the resulting successes have yielded concern over the high rates of multiple pregnancies, which can result in increased maternal and perinatal morbidity and mortality as well as increased health care utilization and costs.
One serum blood test is sufficient to diagnose hyperprolactinemia, and dynamic testing of prolactin secretion should be avoided, according to new guidelines published in the February issue of the Journal of Clinical Endocrinology & Metabolism.
Emotional distress some women experience prior to undergoing fertility treatment appears to have no bearing on the likeihood that the treatment will result in a successful pregnancy, according to a literature analysis published Feb. 23 in BMJ.