OBGYN.net Editorial Advisor
Osteoporosis

Michael Kleerekoper, M.B., B.S., F.A.C.P., F.A.C.E. - USA

Michael Kleerekoper, M.B., B.S., F.A.C.P., F.A.C.E. - USA
Articles and Interviews on OBGYN.net by Dr. Kleerekoper



Office Address:
Department of Internal Medicine
Wayne State University School of Medicine
Division of Endocrinology
4201 St. Antoine, UHC-4H
Detroit, MI 48201

Telephone: (313) 745-3320
Fax: (313) 993 0903

Personal Data:

Place of Birth: Leeds, England
Date of Birth: August 18, 1944
Citizenship: United States
Married with 4 children

Education:
The University of Sydney, Australia (1967) - B.Sc. (Med) - Honors II
The University of Sydney, Australia (1970) - M.B., B.S.

Training:

Postgraduate:
Resident Medical Officer, The Royal North Shore Hospital, Sydney, Australia (1970)
Postgraduate Research Scholar (National Health and Medical Research Council), Department of Medicine, The University of Sydney, Australia (1971-1974)
Fellow in Endocrinology and Metabolism, Washington University School of Medicine and The Jewish Hospital of St. Louis, Missouri (1974-1976)

Faculty Appointments:
Professor, Department of Internal Medicine, Obstetrics and Gynecology, and Pathology (with tenure), Wayne State University School of Medicine. (1997-present)
Professor of Medicine and Obstetrics & Gynecology (with tenure), Wayne State University School of Medicine (1993-present)
Professor of Medicine (with tenure), Case Western Reserve University School of Medicine (1992-1993)
Clinical Associate Professor I, Internal Medicine, Medical School, The University of Michigan, Ann Arbor, Michigan (1983-1993)
Clinical Assistant Professor, Department of Medicine, The University of Michigan, Ann Arbor, MI (1977-1983)

Professional Appointments:
1994- 1996 Associate Chairman, Department of Internal Medicine, Wayne State University, Detroit, MI
1994- 1996 Deputy Specialist-in-Chief, Internal Medicine, Detroit Medical Center, Detroit, MI
1993- Director, Bone and Mineral Metabolism and Gerontology Research, Department of Internal Medicine, Division of Endocrinology and Metabolism, Wayne State University
1985-1993 Division Head, Bone and Mineral Division, Henry Ford Hospital, Detroit, MI
1976-1993 Deputy Director, Bone and Mineral Research Lab, Henry Ford Hospital, Detroit, MI
1990-1993 Director, Center for Osteoporosis Research (Henry Ford Hospital, Southfield, MI
1987-1989 Director of Research, General Internal Medicine
1976-1985 Staff Physician, Bone and Mineral Division, Henry Ford Hospital, Detroit, MI
1979-1982 Director, Clinical Research Unit, Henry Ford Hospital, Detroit, MI

Major Professional Societies:
American Association of Clinical Chemistry1,2
American Association for Clinical Endocrinology1
American Federation for Clinical Research
American Medical Association
American Society for Bone & Mineral Research1,2
Central Society for Clinical Research
International Bone and Mineral Society2
Michigan State Medical Society1
New York Academy of Science
The Endocrine Society2
The Society for Clinical Trials
The American Geriatrics Society
Wayne County Medical Society1

1 Committee member
2 Editorial board, Society Journal

Honors & Awards:
Fellow, American College of Physicians (1980)
Member, Central Society for Clinical Research (1990)
Fellow, American College of Endocrinology (1995)
Member (by election), American Clinical and Climatologic Association (1997)

Service:

1. Patient Care
1976 - 1993 Senior Staff Physician, Henry Ford Medical Group and Henry Ford Hospital
1993 - Physician, Division of Endocrinology and Metabolism, Detroit Medical Center
1994 - 1996 Deputy Physician-in-Chief, Detroit Medical Center

2. Professional Consultation
a. Public Presentations:
1987 Presentation to NIH consensus development conference on osteoporosis
1994 Presentation to NIH consensus development conference on optimal calcium intake
1987, 1989, 1991 Presentation to FDA metabolic diseases advisory panel
1997, Presentation to National Academy of medicine conference on stress fractures in the military

b. Testimony before public bodies
Florida Board of Medicine, July 1996 re bone mass measurement

c. Consulting to public agencies, foundations, professional associations
Chairman, Clinical Skeletal Focus Group, NIDR (1997)
Consultant, WHO-ILAR conference on Minimal Standards for Osteoporosis, Santiago, Chile (1996)
Ad Hoc Reviewer - NIH (1984-1996)
Ad Hoc NIH Study Section - Small Grants in Aging (1985)
Ad Hoc Reviewer - VA (1987,1989)
Medical Research Council Canada (1987)
Medical Research Council New Zealand (1992)
Ad Hoc Reviewer, Department of Defense Osteoporosis Research Grants (Panel Chair) (1997)

d. Consulting to private enterprises
Ad Hoc Consultant to Alza, Merck, Organon, Rhone Poulenc Rorer, Sanofi, Wyeth Ayerst pharmaceutical companies (1989-)
Ad Hoc Consultant to Hologic, CompuMed, Metra Biosystems, Hybritech, Bioquant, Osteodyne Technical Companies (1989-)
Scientific Advisory Board, CompuMed, Manhattan Beach, CA (1992-)
Chairman, Clinical Advisory Committee, Metra Biosystems, Mountain View, CA (1995-)
Scientific Advisory Board, Bone Measurement Institute, Merck & Co., West Point, PA (1995-)
Scientific Advisory Board, Merck-Medco (1996- 1998)
Scientific Advisory Board, Pacific Biometrics (1996-)
Chairman, Scientific Advisory Board, Norland Medical Systems (1997-)

3. Journal/Editorial Activity

a. Reviewer for Medical Journals
American Journal of Medicine
Annals of Internal Medicine
Journal of Clinical Endocrinology Metabolism
Mineral and Electrolyte Metabolism
Radiology
Bone and Mineral
Bone
American Journal of Physiology
American Journal of Medical Sciences
Endocrine Reviews
Journal of American Medical Association
New England Journal of Medicine
Journal of Clinical Investigation
Journal of Dental Research
Calcified Tissue International
Journal of Bone and Mineral Research
Journal of Clinical Densitometry

b. Editorial board memberships
Calcified Tissue International (1988-1993)
Bone (1989-)
Journal of Bone & Mineral Research (1990-1996)
Osteoporosis International (1990-)
Clinical Chemistry (1994-)
Journal of Clinical Endocrinology and Metabolism (1996-)
Osteoporosis: Index & Review (1996-)

4. Other professionally related service
Member, Scientific Review Committee, Michigan Chapter, National Kidney Foundation (1983)
American College of Physicians: Michigan Regional Chapter: Annual Meeting Program Committee (1982-1987)
USPHS Panel on Non-Dental Toxicity of Fluoride (1983)
Member, Steering Committee for the International Symposium on Clinical Disorders of Bone & Mineral Metabolism (May, 1983)
Chairman, International Symposium on Clinical Disorders of Bone and Mineral Metabolism (May, 1988 and May, 1993)
Detroit Medical Club, Secretary (1995)
President-elect (1996)
President (1997)

5. National and international boards and committees

a. Positions held in professional associations
Clinical Chemistry: Educational Committee (Endocrine Subcommittee 1987-1988), Arnold O Beckman Conference Committee (1996-)
American Society for Bone & Mineral Research: Education Committee (1984-); Program Committee (1989 -), nominating committee (1996)
National Osteoporosis Foundation: Member, Scientific Advisory Board (1991-)
Member, Board of Trustees (1996-)
American Association of Clinical Endocrinologists: Clinical Practice, Standards, Guidelines and Therapeutics Committee (1996 -)
Michigan Consortium For Osteoporosis (Founder and Member Steering Committee)

b. Memberships/offices held in public agencies related to discipline
Henry Ford Hospital:
Main Campus Advisory Board of Trustees (1984-1992)
Medical Board: Delegate (1978-1982),
Chairman-elect (1982-1984)
Chairman (1984)
Graduate Medical Education Committee (1982-1992)
Continuing Medical Education Committee (1989-1990)
Bone & Joint Specialty Center Executive Committee (1987-1993)
Editorial Board, Henry Ford Hospital Medical Journal (1982-1992)
Advisory Committee on Physician Compensation & Benefits (1983-1986)

Case Western Reserve University:
Committee on Appointments, Promotions and Tenure, Henry Ford Hospital Campus, Chairman (1992-1993)
Committee on Appointments, Promotions and Tenure (1992-1993)

Wayne State University
Institute of Gerontology, Advisory Board (1994-)
Department of Medicine, Research Committee, (1994-)
Dean’s GME Committee (1995-1996)

Harper Hospital
QE/CRM Committee (1994-1997)

Detroit VAMC
Dean’s Committee (1994-1996)

DMC Care
PSO Operating Board (1995-)

6. State and local boards and committees:
Michigan State Medical Society Committee on Aging (1995-)
Wayne County Medical Society
Education Committee (1983-94), Chairman 1993-1999
Ethics Committee (1993-1996)
Medical-Legal Committee (1992-1997)
WCMS Executive Council (1998-1999)
Membership Committee (1995-1996)

Teaching

1. Years at Wayne State: Four

2. Years at other colleges/universities:
University of Michigan (1983-1993)

3. Courses taught at Wayne State in last five years:
a. Undergraduate:
None.
b. Graduate: None.
c. Graduate Professional:
03/27/91 Current Concepts in Post-Menopausal Hormone Replacement Therapy The Dearborn Inn, Dearborn, MI
04/08/92 Current Concepts in Post-Menopausal Hormone Replacement Therapy, Eberhard Conference Center, Grand Rapids, MI
10/21/92 Current Concepts in Prevention and Management of Post-Menopausal Osteoporosis, The Dearborn Inn, Dearborn, MI
11/04/92 Endocrinology Review Course, The Fairlane Club, Dearborn, MI
11/06/94 Endocrinology Review Course, The Fairlane Club, Dearborn, MI

d. Medical Students: 2nd Year Pathophysiology, 1994 -
2nd Year Physical Diagnosis, 1994 -
3rd Year Internal Medicine, Endocrinology, 1994 -

e. Residents/Fellows: Elective Rotation for Endocrine Fellows (1992-1993) General Internal Medicine Rounds(1994-) Endocrine Rounds(1995-)
Professor’s Rounds (coordinator)(1994 -)

4. Essays/Theses/Dissertations directed: None.

Course or curriculum development: "Critical thinking in clinical science". A bi-monthly course for Internal Medicine residents, scheduled to begin in September 1995. The course is designed to teach participants how to properly integrate the skills needed for all aspects of patient care with those needed for patient oriented research.

Biomedical Engineering, (BME # 525): Developed a one semester curriculum on Osteoporosis and Fractures in conjunction with Dorothy Nelson, Ph. D.

Publications:

1. Original observations in refereed journals

2. Review Articles

1. Posen S, Cornish CJ, Kleerekoper M: Alkaline phosphatase in the diagnosis of metabolic bone disorders. In: Parfitt AM, Frame B, eds. Proc of International Symposium on Clinical Aspects of Metabolic Bone Disease. Amsterdam: Excerpta Medica 74-79, 1973.

2. Parfitt AM, Mathews M, Rao DS, Kleerekoper M: The regulation of 25-hydroxylation by vitamin D intake in man: A theoretical model. In: Norman AW et al, eds. Vitamin D: Basic research and its clinical application. Berlin: Walter DeGruyter, 496-500, 1979.

3. Kleerekoper M, Cruz C, Bernstein RS, Levin NW, Foreback CC, Parfitt AM: The phosphaturic action of PTH in the steady state in patients with normal and impaired renal function. Phosphate and Minerals in Health and Disease. Adv Exp Med Biol 128:145-154, 1980.

4. Parfitt AM, Rao DS, Kleerekoper M, Walczak N. Levin N, Oliver I, Frame B: Proximal and distal radial bone mineral measurement in primary and secondary hyperparathyroidism: Diagnostic value and response to treatment. In: Mazess RB, ed. Proc. for the Fourth International Conference on Bone Mineral Measurement. NIH Publication, 80-1938:183-190, 1980.

5. Zinn D, Cruz C, Smith D, Potocki M, Parfitt C, Hricak H, Levin NW, Kleerekoper M: Reduction in dialysate calcium concentration lowers skin calcium content in patients on chronic hemodialysis. Trans Am Soc Artif Inten Organs 26:378-382, 1980.

6. Kleerekoper M, Bernstein RS, Rao Ds, Frame B, Levin NW, Parfitt AM: Parathyroid hormone, phosphate and the kidney. Prog Biochem Pharmacol 17:190-198, 1980.

7. Parfitt AM, Rao DS, Kleerekoper M, Walczak N. Levin N, Oliver I, Frame B: Midshaft and distal radius bone mineral in primary and secondary hyperparathyroidism: Diagnostic value and response to treatment. Proceedings of the Fourth International Conference on Bone Measurement, 1980. US Dept. H.H.S. NIH 80-1938, Bethesda, 183-190.

8. Parfitt AM, Mathews C, Rao D, Frame B, Kleerekoper M, Villanueva AR: Impaired osteoblast function in metabolic bone disease. In: Deluca HF, Frost H, Jee W, Johnston C, Parfitt AM, eds. Osteoporosis: Recent Advances in Patho-genesis and Treatment. Baltimore: University Park Press, 321-330, 1981.

9. Kleerekoper M, Frame B, Villanueva AR, Oliver I, Rao DS, Matkovic V, Parfitt AM: Treatment of osteoporosis with sodium fluoride alternating with calcium and vitamin D. In: Deluca HF, Frost H, Jee W, Johnston C, Parfitt AM, eds. Osteoporosis: Recent Advances in Pathogenesis and Treatment. Baltimore: University Park Press 441-448, 1981.

10. Kleerekoper M, Oliver I, Frame B, Rao DS, Villanueva AR, Parfitt AM: Adverse effect of Vitamin D in fluoride treated osteoporosis. Veterinary and Human Toxicology 24:388, 1982.

11. Kleerekoper M, Bernstein RS, Cruz C, Levin NW, Parfitt AM: Parathyroid hormone resistance in renal allograft recipients. In: Massry SG, Letteri JM, Ritz E, eds. Proc 5th International Workshop on Phosphate and Other Minerals Regulations of Phosphate and Mineral Metabolism. Adv Exp Med Biol 151:185-187, 1982.

12. Kleerekoper M, Parfitt AM: Skeletal histology in osteoporosis: Effect of fluoride therapy. Proc in the Int Fluoride Symposium, Utah State University, Logan, Utah, May 1982.

13. Kleerekoper M: The management of primary hyperparathyroidism. Overview. In: Frame B, Potts J Jr, eds. Clinical Disorders of Bone and Mineral Metabolism. Amsterdam: Excerpta Medica, 149-151, 1983.

14. Kleerekoper M, Villanueva AR, Mathews CHE, Rao DS, Pumo B, Parfitt AM: PTH mediated bone loss in primary and secondary hyperparathyroidism. In: Frame B, Potts J Jr, eds. Clinical Disorders of Bone and Mineral Metabolism. Amsterdam: Excerpta Medica, 200-203, 1983.

15. Rao DS, Villanueva A, Mathews M, Pumo B, Frame B, Kleerekoper M. Parfitt AM: Histologic evolution of vitamin D depletion in patients with intestinal malabsorption or dietary deficiency. In: Frame B, Potts J Jr, eds. Clinical Disorders of Bone and Mineral Metabolism. Amsterdam, Excerpta Medica, 224-226, 1983.

16. Parfitt AM, Mathews CHE, Villanueva AR, Rao DS, Rogers M, Kleerekoper M, Frame B: Microstructural and cellular basis of age related bone loss and osteoporosis. In: Frame B, Potts J Jr, eds. Clinical Disorders of Bone and Mineral Metabolism. Amsterdam, Excerpta Medica, 328-332, 1983.

17. Talpos GE, Kleerekoper M, Kambouris A, Morre DR: Management of primary hyperparathyroidism. Report on workshop. Frame B, Potts J Jr, eds. Clinical Disorders of Bone and Mineral Metabolism. Amsterdam, Excerpta Medica, 537-539, 1983.

18. Rao DS, Marel G, Wong K. Zonca M, Kleerekoper M, Frame B, Parfitt AM: Reversible and irreversible skeletal disease in adult coeliac disease. In: Chon DV, Potts JT Jr, Fujita T, eds. Endocrine control of bone and calcium metabolism. Elsevier Science Publishers B.V., 279-280, 1984.

19. Kleerekoper M: Controlled clinical trials in osteoporosis. Proceedings of the workshop on the Coherence Therapy for Osteoporosis, February 10-11, 1984.

20. Kleerekoper M, Parfitt AM, Ellis BI: Measurement of vertebral fracture rates in osteoporosis. In: Christiansen C, Arnaud CD, Nordin BEC, Parfitt AM, Peck WA, Riggs BL, eds. In: Osteoporosis: Proc Copenhagen Int Symposium on Osteoporosis, June 3-8, 1984. Aalborg Stiftsbogtrykkeri, pp 103-109.

21. Parfitt AM, Kleerekoper M: Diagnostic value of bone histomorphometry and comparison of histologic measurements and biochemical indices of bone remodeling. In: Christiansen C, Arnaud CS, Nordin BEC, Parfitt AM, Peck WA, Riggs BL, eds. In: Osteoporosis. Proc Copenhagen Int Symposium on Osteoporosis, June 3-8, 1984. Aalborg Stiftsbogtrykkeri, pp. 111-120.

22. Kleerekoper M, Parfitt AM, Ellis BI: Measurement of vertebral fracture rates in osteoporosis. In: Christiansen C, Arnaud CD, Nordin BEC, Parfitt AM, Peck WA, Riggs BL, eds. Osteoporosis. Proc Copenhagen Int Symposium on Osteoporosis, June 3-8, 1984. Aalborg Stiftsbogtrykkeri, pp. 103-109.

23. Kleerekoper M: Are there different types of osteoporosis and does it matter? In: Posen S, ed. A discussion on the diagnosis and treatment of osteoporosis. Bern, Hans Huber Publishers, 51-55, 1986.

24. Kleerekoper M: The prevention of postmenopausal osteoporosis with estrogen: Treating the menopause as an endocrine deficiency state. ASBMR Workshop, 1986.

25. Kleerekoper M, Feldkamp LA, Goldstein SA: The effect of aging on the skeleton - implications for changes in tolerance. In: Biomechanics and Medical Aspects of Lower Limb Injuries. Society of Automotive Engineers Inc., Warrandale, PA. pp 91-96, 1986.

26. Kleerekoper: Primary hyperparathyroidism. In: Proceedings of the International Symposium on Metabolic Bone Diseases in Osteoporosis, Santiago, Chile, April 17-19, 1986.

27. Kleerekoper M: Selected laboratory procedures in patients with clinical disorders of bone and mineral metabolism. In: Proceeding of the International Symposium on Metabolic Bone Diseases in Osteoporosis, Santiago, Chile, April 17-19, 1986.

28. Kleerekoper M: Clinical disorders of calcium homeostatic - an overview. In: Proceedings of the International Symposium on Metabolic Bone Diseases in Osteoporosis, Santiago, Chile, April 17-19, 1986.

29. Kleerekoper M: Osteoporosis. In: Proceedings of the International Symposium on Metabolic Bone Diseases in Osteoporosis, Santiago, Chile, April 17-19, 1986.

30. Parfitt AM, Rao DS, Kleerekoper M, Villanueva AR: Increased bone age: Mechanisms and consequences. IN: Christiansen C, Johansen C, Riis BJ, eds. Osteoporosis 1987. Osteopress Aps, Copenhagen, pp 301-308.

31. Kleerekoper M, Dickie D, Feldkamp LA, Goldstein SA, Flynn MJ, Parfitt AM: Cancellous bone architecture and bone strength. In: Christiansen C, Johansen C, Riis BJ, eds. Osteoporosis 1987. Osteopress Aps, Copenhagen, pp 294-300.

32. Kleerekoper M: Experimental therapeutic strategies to increase bone mass. Postgraduate Medicine 1989- A special report: Long-term effects of estrogen deprivation. pp 26-28, 1989.

34. Balena R, Flynn MJ, Foldes J, Parfitt AM, Kleerekoper M: Application of Image Analysis in Metabolic Bone Diseases. In: Guardabasso V, Rodbard D, Forti G, eds. Computers in Endocrinology: Recent Advances. pp 159-170, 1990.

35. Parfitt AM, Villanueva AR, Rao D, Kleerekoper M: Remodeling mechanisms that contribute to bone loss and fracture. Proceedings from the Fifth International Congress on Bone Morphometry 1990. Bone Morphometry. Nishimura Co LTD, Japan, pp 346-354.

36. Kleerekoper M: Non-dental tissue effects of fluoride. Advances in Dental Research 8:32-38, 1994.

37. Edelson GW, Kleerekoper M: Hypercalcemic crisis. Med Clin North Am 79(1):79-92, 1995.

38. Edelson GW, Kleerekoper: Bone mass, bone loss, and fractures. Physical Medicine and Rehabilitation Clinics of North America 6:455-464, 1995.

39. Edelson GW, Kleerekoper M: Biochemical Studies in the Evaluation and Management of Osteoporosis - Current Status and Future Prospects. Endocrine Practice 2:13-19, 1996.

40. Kleerekoper M. Fluoride and the skeleton. Critical Reviews in Clinical Laboratory Sciences 33:139-161, 1996.

41. Kleerekoper M. Biochemical markers of bone remodeling. Am J Med Sci 312:270-277, 1996.

3. Books and Chapters

1. Posen S, Cornish CJ, Kleerekoper M; Alkaline phosphatase and metabolic bone disease. In: Avioli LV, Krane SM, eds. Metabolic Bone Disease. New York: Academic Press, 141-181, 1977.

2. Kleerekoper M: Osteomalacia and rickets. In: Tice's Practice of Medicine New York: Harper Row. Chapter 51, 1979.

3. Parfitt AM, Kleerekoper M: The divalent ion homeostatic system. Physiology and metabolism of calcium, phosphorus, magnesium and bone. In: Maxwell M, Kleeman CR, eds. Clinical Disorders of Fluid and Electrolyte Metabolism, 3rd ed. New York: McGraw Hill, pp 269-398, 1980.

4. Parfitt AM, Kleerekoper M: Clinical disorders of calcium, phosphorus and magnesium metabolism. In: Maxwell M, Kleeman Cr, eds. Clinical Disorders of Fluid and Electrolyte Metabolism, 3rd ed. New York: McGraw Hill, pp 947-1151, 1980.

5. Frame B, Kleerekoper M: Rickets and osteomalacia. In: Conn HF, ed. Current Therapy. Philadelphia: W.B. Sanders, 447-451, 1980.

6. Kleerekoper M: Laboratory evaluation in patients with abnormal bone and mineral homeostasis. In: Stein JH, ed. Internal Medicine: A Systematic Approach. Boston: Little, Brown & Co, 1829-1836, 1983.

7. Kleerekoper M: Paget's Disease. In: Spittell JA Jr, ed. Clinical Medicine. Philadelphia, Harper & Row, 1984.

8. Kleerekoper M, Rao DS: Hypercalcemia and hypocalcemia. In: Callaham M, ed. Current Therapy in Emergency Medicine. B.C. Decker, Inc, 729-732, 1986.

9. Clinical Disorders of Bone and Mineral Metabolism. Michael Kleerekoper and Stephen M. Krane editors. Mary Ann Liebert, Inc. New York, publishers. pp 1-649, 1989.

10. Kleerekoper M and Gaasch W: "Hypercalcemia and Hypocalcemia" in Decision Making in Emergency Medicine. J. Callahan, Ed. B.C. Decker Inc. Publisher: Philadelphia, pp 168-169, 1990.

11. Primer on the Metabolic Bone Diseases and Diseases of Mineral Metabolism: MJ Favus, ed., M Kleerekoper, associate ed., American Society for Bone and Mineral Research, Publisher.
First edition 1990.
Second edition 1993. Raven Press, publisher.
Third edition 1996. Raven Press, publisher (in preparation).

12. Kleerekoper M, Avioli LV: Evaluation and treatment of postmenopausal osteoporosis. In: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. MJ Favus, ed., American Society for Bone and Mineral Research, publisher, pp 151-154, 1990.

13. Kleerekoper M, Avioli LV: Evaluation and treatment of postmenopausal osteoporosis. In Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 2nd edition. MJ Favus, Ed. Raven Press, publisher, pp.223-229,1993.

14. Kleerekoper M, Avioli LV: Evaluation and treatment of postmenopausal osteoporosis. In Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 3rd edition. MJ Favus MJ, Ed. Raven Press, publisher, pp.264-271, 1996

15. Kleerekoper M, Rao DS, Talpos G, Bone H: Management of Asymptomatic Primary Hyperparathyroidism. Advances in Endocrinology and Metabolism, Vol 2, pp 205-220, 1991.

16. Edelson G, Kleerekoper M: Hyperparathyroidism and Hypoparathyroidism in Conn's Current Therapy. RE Rakel, Ed. WB Saunders publishers, pp 559-565, 1992.

17. Kleerekoper M, Mendlovic D: Osteoporosis in Conn's Current Therapy, RE Raken Ed, WB Saunders publishers, pp 566-570, 1993.

18. Kleerekoper M, Balena R: Fluorides and Osteoporosis in Annu Rev Nutr. R Olson Ed, AR CA Publishers, 11:309-24, Vol II, 1991.

19. Kleerekoper M: Fluoride in "Osteoporosis" J.C. Stevenson, R. Lindsay, Eds. Chapman and Hall, London (in press).

20. Kleerekoper M: Clinical Course of Primary Hyperparathyroidism, in "The Parathyroids. Basic and Clinical Concepts." J.P. Bilezikian, M.A. Levine, R. Marcus, Eds. Raven Press, New York pp.471-483, 1994.

21. Nelson DA, Kleerekoper M. Perspectives on morphometric and qualitative vertebral fracture assessment. In AVertebral Fracture in Osteoporosis@, HK Genant, M Jergas, C van Kuijk Eds., Radiology Research and Education Foundation, San Francisco, publishers. pp.361-70, 1995

22. Nelson DA, Kleerekoper M. What is a vertebral fracture. In AOsteoporosis@, R Marcus, D Feldman, J Kelsey Eds. Academic Press, San Diego, publisher, pp.613-621, 1996

23. Kleerekoper M: The evaluation of patients with osteoporosis. in AOsteoporosis@, R Marcus, D Feldman, J Kelsey Eds. Academic Press, San Diego, publisher, pp1011-8, 1996

24. Kleerekoper M: The epidemiology of osteoporosis. In "Osteoporosis: Diagnostic and therapeutic principles" CJ Rosen ed. Humana Press Totowa, New Jersey, publishers pp. 65-68, 1996

25. Edelson GW, Kleerekoper M: Pathophysiology of osteoporosis. In "Osteoporosis: Diagnosis and treatment", DJ Sartoris ed, Marcel Dekker, Inc., New York, publishers. pp. 1-18, 1996

26. Kleerekoper M.: Fluoride and the skeleton. in, "Principles of Bone Biology", JP Bilezikian, LG Raisz, GA Rodan eds., Academic Press, San Diego, publishers. pp. 1053-1062, 1996

27. Kleerekoper M, Avioli LV: Osteoporosis Pathogenesis and Therapy. In: "Metabolic Bone Disease and Clinically Related Disorders" LV Avioli and SM Krane (eds.), Academic Press 3rd edition, San Diego, publishers pp 387-409, 1997

28. Kleerekoper M, DA Nelson: Differential Diagnosis: Low Bone Mass. In "Osteoporosis in Clinical Practice: A Practical Guide for Diagnosis and Treatment" P Geusens (ed) Springer-Verlag Berlin Heidelberg New York publishers pp 73-76, 1997

29. Igwe R, M Kleerekoper: Endocrine & Hemoglobin-Related Arthropathies & Storage Diseases: Bone and Joint Abnormalities in Thyroid Disease. In "Rheumatology Second Edition, JH Klippel and PA Dieppe (eds) Mosby International, London, publishers pp 21.1-21.4, 1997

30. Kleerekoper M, R Igwe: Endocrine & Hemoglobin-Related Arthropathies & Storage Diseases: Hyperparathyroidism. In Rheumatology Second Edition, JH Klippel and PA Dieppe (eds) Mosby International, London, publishers pp (8)22.1-22.4, 1997

31. Kleerekoper M, Nelson DA: Fluoride therapy for Postmenopausal osteoporosis. In: Osteoporosis (eds) John C. Stevenson and Robert Lindsay, published by Chapman & Hall, London pp 277-292, 1998

32. Kleerekoper M, Nelson DA: Peripheral bone densitometry: an old friend revisited. In: Transactions of the American Clinical and Climatological Association, Vol 109, pp 62-72, 1998.

Published abstracts: (for last seven years)

Presentations:

1. Invited and/or refereed international or national meetings
1994 American Diabetes Association Postgraduate Assembly
invited symposium presentation

International Rehabilitation Medicine Association
invited symposium presentation

Endocrine Society Annual Meeting
invited symposium presentation

American Association for Clinical Chemistry Annual Meeting
invited workshop participant

First Annual Los Angeles Briefing on Women=s Health Problems
invited panelist

Brazilian Endocrine Society
invited plenary lecturer

Chilean Rheumatology Society
invited plenary lecturer

1995 Clinical Ligand Society Annual Meeting
invited workshop moderator and speaker

American Association for Clinical Chemistry Annual Meeting
invited workshop presentation
invited breakfast and lunch roundtable discussion leader

American Society for Bone and Mineral Research Annual Meeting
meet the professor roundtable discussion leader

International Society for Clinical Enzymology
invited plenary lecture

Second Annual Los Angeles Briefing on Womens Health Problems
invited panelist

1996 American Association for Clinical Chemistry Annual Meeting
invited workshop presentation
invited Edu-track presentation

American Society for Reproductive Medicine Annual Meeting
invited workshop presentation

International Society for Clinical Densitometry Annual Meeting
invited plenary lecture

WHO-ILAR conference on minimal standards for osteoporosis
invited lecture

American College of Obstetrics and Gynecology Annual Meeting
invited workshop presentation

American College of Obstetrics and Gynecology Region VI annual meeting
invited lecture

American Association for Rehabilitation Medicine Annual Meeting
invited workshop presentation

2. Invited and/or refereed local/regional meetings

3. Invited seminars or lectures presented

1992 Lectures:

1993 Lectures

1994 Lectures

1995 Lectures

1996 Lectures

1997 Lectures

1998 Lectures